Background: Low Back Pain (LBP) is the leading cause of disability in the world. This study aimed to evaluate the effect of acupressure on LBP intensity and depression among Chronic nonspecific LBP patients. Methods: This sham-controlled randomized clinical trial was performed on 84 patients with Chronic nonspecific LBP. The data were collected using a demographic information questionnaire, the Visual Analogue Scale (VAS), and the Beck Depression Inventory-II (BDI-II). The participants were randomly assigned to acupressure (n = 42) and sham (n = 42) groups. The acupressure group was trained on how to apply pressure on Yin tang, Feng Chi, and Shu Fu acupoints,nevertheless, the sham group was trained on how to apply pressure on Chen Jiang, Huang Shu, and Ji ache acupoints. The participants in both groups applied acupressure once a day for 4 weeks. Both groups completed the VAS and the BDI-II again one day after the intervention. Results: No significant differences in LBP intensity (P = 0. 45) and depression (P = 0. 26) were observed between the two groups before the intervention. By controlling the baseline scores of LBP and depression, analysis of covariance revealed that the LBP and depression of the acupressure group significantly improved after the intervention, compared to the sham group (P < 0. 05). Conclusions: Applying pressure on Shu Fu, Yin Tang, and Feng Chi points is effective in reducing LBP and depressionamongChronic nonspecific LBP patients. The findings of this study can be used in designing and evaluating more robust protocols.

Background: The Multiwave Locked System (MLS) has been shown to reduce inflammation and enhance biostimulation. Objectives: The aim was to investigate the effect of using MLS laser in reducing Pain severity in patients with Chronic Back Pain. Methods: This randomized double-blind study was conducted on 30 patients (15 in each group) with Chronic Low Back Pain (LBP) who were referred to Imam Khomeini Hospital and diagnosed by a physical medicine specialist based on diagnostic criteria. The intervention group was treated with MLS multiple wave laser, performed 12 times, with patients receiving laser treatment twice a week. The control group was treated with exercise therapy. Pain intensity was evaluated using the Visual Analog Scale (VAS) before treatment and 6 weeks after treatment. Pain was analyzed before and after the intervention, both within and between groups. Results: Of the 30 evaluated patients, the mean and standard deviation of age (P = 0.392) and gender (P = 0.666) were not statistically significant between the two groups. The VAS value before treatment in the intervention and control groups was 7.66 ± 1.11 and 7.73 ± 1.16, respectively (P = 0.794). After treatment, the VAS values in the MLS and control groups were 5.60 ± 1.35 and 7.73 ± 1.16, respectively. Statistical evaluation showed a statistically significant difference between the two groups (P = 0.001), and the total change in VAS values was significant (P = 0.001). Conclusions: Multiwave Locked System laser can reduce the Pain severity of Chronic LBP, with the reduction rate in the intervention group being significantly higher than in the exercise group.